Note that in Quadrant II and in Quadrant IV, the x- and y-values have opposite signs. Therefore, to satisfy the required condition, the solutions to the system of inequalities must lie in either Quadrant II or IV. Consider the following system.
x<0 & (I) y>0 & (II)
Let's graph the system!
This is easier to see if we cut away the shading where the inequalities do not overlap.